Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.Tocchetti A., Genomics 81:234-244(2003).Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).Offenhaeuser N., Mol. Biol. Cell 15:91-98(2004).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human ES8L2.
