The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.Ramos S., Gene 298:147-157(2002).Nagase T., DNA Res. 5:277-286(1998).Nakajima D., DNA Res. 9:99-106(2002).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human RHBT2.
