Involved in down-regulation of the androgen receptor (AR). Enhances ubiquitination and proteasome-mediated degradation of AR, probably by recruiting NEDD4.Xu L.L., Genomics 66:257-263(2000).Rae F.K., Mol. Carcinog. 32:44-53(2001).Deloukas P., Nature 414:865-871(2001).
应用类型
WB,IHC,ICC
免疫原
Synthesized peptide derived from internal of human TMEPA.
