General activator of RNA polymerase which utilizes different TFIIIB complexes at structurally distinct promoters. The isoform 1 is involved in the transcription of tRNA, adenovirus VA1, 7SL and 5S RNA. Isoform 2 is required for transcription of the U6 promoter.Wang Z., Proc. Natl. Acad. Sci. U.S.A. 92:7026-7030(1995).Mital R., Mol. Cell. Biol. 16:7031-7042(1996).McCulloch V., EMBO J. 19:4134-4143(2000).
应用类型
WB,IHC,ICC
免疫原
Synthesized peptide derived from internal of human TF3B.