Ras effector protein that functions as a guanine nucleotide exchange (GEF) for RAB5B and RAB31, by exchanging bound GDP for free GTP. Required for normal RAB31 function.Heilig R., Nature 421:601-607(2003).Ota T., Nat. Genet. 36:40-45(2004).Saito K., J. Biol. Chem. 277:3412-3418(2002).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human RIN3.
