Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression By similarity.Carlsson R., Gene 299:271-278(2002).The MGC Project Team, Genome Res. 14:2121-2127(2004).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human SPIC.
