DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK6 promotes Ret-mediated neurite growth. May have a role in brain development and/or maintenance.Crowder R.J., J. Biol. Chem. 279:42072-42081(2004).The MGC Project Team, Genome Res. 14:2121-2127(2004).Ota T., Nat. Genet. 36:40-45(2004).
应用类型
WB,ICC
免疫原
Synthesized peptide derived from internal of human DOK6.
