Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits JUN/AP1 and NF-kappa-B activation. Promotes Fas-induced apoptosis By similarity.Chen Y.H., Cell 133:415-426(2008).Sugano S., Nat. Genet. 36:40-45(2004).Schupp I., BMC Genomics 8:399-399(2007)
应用类型
WB
免疫原
Synthesized peptide derived from internal of human TNFAIP8L2.
