Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival By similarity. Activates ENaC (in vitro).Underwood L.J., Biochim. Biophys. Acta 1502:337-350(2000).Scott H.S., Nat. Genet. 27:59-63(2001).Clark H.F., Genome Res. 13:2265-2270(2003).
应用类型
WB,ICC
免疫原
Synthesized peptide derived from C-terminal of human TMPRSS3.