Potent transcriptional repressor that binds to the H1 element of the Ets2 promoter. May regulate other genes involved in cellular proliferation. Required for extraembryonic ectoderm differentiation, ectoplacental cone cavity closure, and chorioallantoic attachment By similarity. May be important for regulating trophoblast stem cell differentiation By similarity.Sgouras D.N., EMBO J. 14:4781-4793(1995).Grimwood J., Nature 428:529-535(2004).Olsen J.V., Cell 127:635-648(2006).
应用类型
IHC
免疫原
Synthesized peptide derived from internal of human ERF.
