Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.Peterson M.G., Nature 354:369-373(1991).Sumimoto H., Nature 354:401-404(1991).Kang S.-W., Genes Cells 5:251-263(2000).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human TF2E2.