Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform mayact as a negative regulator of normal cell cycle progression.Bunnell B.A., Proc. Natl. Acad. Sci. U.S.A. 87:7467-7471(1990).Eipers P.G., Genomics 13:613-621(1992).Xiang J., J. Biol. Chem. 269:15786-15794(1994).
应用类型
WB
免疫原
Synthesized peptide derived from N-terminal of human CD2L1.
