Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.Jantzen H.M., Nature 344:830-836(1990).Chan E.K.L., J. Exp. Med. 174:1239-1244(1991).Molina H., Proc. Natl. Acad. Sci. U.S.A. 104:2199-2204(2007).
应用类型
WB,IHC
免疫原
Synthesized peptide derived from internal of human UBF1.
