Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.Braun T., EMBO J. 8:701-709(1989).Thompson D.B.; Submitted (MAY-1995) to the EMBL/GenBank/DDBJ databases.
应用类型
WB
免疫原
Synthesized peptide derived from inetrnal of human MYF5.