Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site By similarity. Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling.Candau R., Mol. Cell. Biol. 16:593-602(1996).Ogryzko V.V., Cell 94:35-44(1998).Henriksson A., Mol. Cell. Biol. 17:3065-3073(1997).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human ADA2L.
