Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.Cole K.A., Genomics 51:282-287(1998).Babu E., J. Biol. Chem. 278:43838-43845(2003).Chuaqui R.F., Urology 50:302-307(1997).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human LAT3.
