Catalytic component of a structure-specific DNA repair endonuclease responsible for the 5-prime incision during DNA repair. Involved in homologous recombination that assists in removing interstrand cross-link.Brookman K.W., Mol. Cell. Biol. 16:6553-6562(1996).Sijbers A.M., Cell 86:811-822(1996).Cleaver J.E., Hum. Mutat. 14:9-22(1999).
应用类型
WB
免疫原
Synthesized peptide derived from internal of human XPF.
