Activates ubiquitin by first adenylating with ATP its C-terminal glycine residue and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Catalyzes the ISGylation of influenza A virus NS1 protein.Sutisak Kitareewan, PNAS, Mar 2002; 99: 3806. Keun Il Kim, Mol. Cell. Biol., Jan 2006; 26: 472 - 479. Ian Pitha-Rowe, Cancer Res., Nov 2004; 64: 8109 - 8115.
应用类型
WB,IHC
免疫原
Synthesized peptide derived from C-terminal of human UBE1L.
