Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.Iwabuchi K., J. Biol. Chem. 273:26061-26068(1998).Nakajima D., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.Bechtel S., BMC Genomics 8:399-399(2007).
应用类型
WB
免疫原
Synthesized peptide derived from Internal of human 53BP1.
