Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.Derijard B.,Science 267:682-685(1995).The MGC Project Team;Genome Res. 14:2121-2127(2004).Lim S.,J. Biol. Chem. 277:25040-25046(2002).
应用类型
WB
免疫原
Synthesized non-phosphopeptide derived from human MAP2K3 around the phosphorylation site of threonine 222 (A-K-T(p)-M-D).
