Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.Ana V. Miletic, J. Biol. Chem., Dec 2006; 281: 38257 - 38265.Christopher C. Stebbins, Mol. Cell. Biol., Sep 2003; 23: 6291 - 6299.Vered Schapira, Cancer Res., Jun 2006; 66: 6183 - 6191.Maya Groysman, J. Biol. Chem., Dec 2002; 277: 50121 - 50130.
应用类型
WB
免疫原
Synthesized non-phosphopeptide derived from human VAV1 around the phosphorylation site of tyrosine 174 (E-I-Y-E-D).