Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.Boyle W J, et al. (1991) Cell. 64(3): 573-584.Binetruy B, et al. (1991) Nature. 351: 122-127.Smeal T, et al. (1991) Nature. 354:494-496.Derijard B, et al. (1994) Cell. 76:1025-1037.Kyriakis J M, et al. (1994) Nature. 369: 156-160.
应用类型
WB,IHC
免疫原
Synthesized non-phosphopeptide derived from human c-Jun around the phosphorylation site of serine 243.