Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.Suzuki S., EMBO J. 9:757-763(1990).Hogervorst F., EMBO J. 9:765-770(1990).Tamura R.N., J. Cell Biol. 111:1593-1604(1990).
应用类型
WB,IHC
免疫原
Synthesized non-phosphopeptide derived from human ITGB4 around the phosphorylation site of tyrosine 1510 (R-D-Y(p)-S-T).
