- 中文名称
GR (Ab-211) 一抗
- 英文名字
- GR (Ab-211) Primary antibody
- 供应商
- Promab
- 产品货号
- PMB-P41636
- 产品报价
- ¥询价/100ul

- 产品说明书
- 点击查看
- 购买方式
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- 产品新闻

- 背景资料
- Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression.Zhen Wang, Mol. Endocrinol., Mar 2007; 21: 625 - 634.Aaron L. Miller, Mol. Endocrinol., Jun 2005; 19: 1569 - 1583.Paul J. LeBlanc, J. Physiol., Jun 2004; 557: 559 - 570.Jos篓娄 Xavier-Neto, Hypertension, Jul 1999; 34: 31.
- 应用类型
- WB,IHC,ICC
- 免疫原
- Synthesized non-phosphopeptide derived from human GR around the phosphorylation site of serine 211 (N-E-S-P-W).
- 来源宿主
- Rabbit
- 反应性
- Human
- 保存建议
- 4℃短期保存;-20℃长期保存。避免冻融循环。
- 其他
- ProMab 生物技术公司通过整合生物信息学、分子生物学、蛋白质表达、纯化技术、基因克隆、微生物学和免疫学,利用新型高通量技术开发重组蛋白、抗体和工程细胞系并将其商业化。专注于免疫治疗领域,特别是 CAR-T/NK 细胞技术。ProMab 还开发了一种新型的 mRNA 脂质纳米颗粒(mRNA-LNP)平台,用于即用型试剂和定制研究服务,以推进现有产品并扩展到更多的研究领域。

- 注意
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