This gene is a member of the G protein-coupled receptor family and is found in the cell membrane. G protein-coupled receptors, characterized by a seven transmembrane domain motif, are involved in translating outside signals into G protein mediated intracellular effects. The encoded protein activates adenylate cyclase and modulates amyloid-beta production in a mouse model, suggesting that it may play a role in Alzheimer's disease.
应用类型
WB,IHC
免疫原
Synthetic peptide corresponding to a region derived from 318-330 amino acids of Human G protein-coupled receptor 3
