Effector protein for Rho-type GTPases. Regulates actin filament reorganization via its interaction with the Arp2/3 complex. Important for efficient actin polymerization. Possible regulator of lymphocyte and platelet function. Mediates actin filament reorganization and the formation of actin pedestals upon infection by pathogenic bacteria.
应用类型
WB
免疫原
Peptide sequence around aa.289~293 (L-I-Y-D-F) derived from Human WASP.