Acts as part of the IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Also phosphorylates NCOA3.
应用类型
WB,ICC
免疫原
Peptide sequence around aa.197~201 (Q-K-Y-T-V) derived from Human IKK-b.
