Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.
应用类型
WB,IHC
免疫原
Peptide sequence around aa.219~223 (A-N-S-F-V) derived from Human MEK1.