proto-oncogenic cytoplasmic tyrosine kinase of the SRC family. Highly expressed in certain fully differentiated cells such as neurons, platelets and macrophages. Phosphorylation of an activation loop tyrosine activates the enzyme; phosphorylation of a tyrosine in the C-terminus by Csk inhibits the enzyme.
应用类型
WB,IHC
免疫原
Peptide sequence around aa. 527~531 (P-Q-Y-Q-P) derived from Human Src.
