Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes
应用类型
WB,IHC,ICC
免疫原
Peptide sequence around aa. 392~396 (E-D-S-G-D) derived from Human HDAC2.
