Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
应用类型
WB,IHC,ICC
免疫原
Peptide sequence around aa.serine 60~64 or 42~46 (N-D-S-V-I) derived from Human ATF2.
