Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of serine 484 (P-E-S(p)-P-K) derived from Human UBF.