Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of Serine 124n(S-H-S(p)-D-S) derived from Human CDC25A.