- 中文名称
BLNK (Phospho-Tyr96) 一抗
- 英文名字
- BLNK (Phospho-Tyr96) Primary antibody
- 供应商
- Promab
- 产品货号
- PMB-P40598
- 产品报价
- ¥询价/100ul

- 产品说明书
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- 购买方式
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- 产品新闻

- 背景资料
- Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. Wang X, et al. (2012)J Biol Chem 287, 11037-48. Patterson HC, et al. (2006)Immunity 25, 55-65 . Chiu CW, et al. (2002)EMBO J 21, 6461-72.
- 应用类型
- WB
- 免疫原
- Peptide sequence around phosphorylation site of tyrosine 96(D-S-Y(p)-E-P) derived from Human BLNK .
- 来源宿主
- Rabbit
- 反应性
- Human
- 保存建议
- 4℃短期保存;-20℃长期保存。避免冻融循环。
- 其他
- ProMab 生物技术公司通过整合生物信息学、分子生物学、蛋白质表达、纯化技术、基因克隆、微生物学和免疫学,利用新型高通量技术开发重组蛋白、抗体和工程细胞系并将其商业化。专注于免疫治疗领域,特别是 CAR-T/NK 细胞技术。ProMab 还开发了一种新型的 mRNA 脂质纳米颗粒(mRNA-LNP)平台,用于即用型试剂和定制研究服务,以推进现有产品并扩展到更多的研究领域。

- 注意
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