CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain. Goshima Y., Nature 376:509-514(1995)Hamajima N., Gene 180:157-163(1996)Kitamura K., DNA Res. 6:291-297(1999)
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of Serine 522(K-T-S(p)-P-A) derived from Human CRMP-2.
