Transcriptional modulator activated by TGF-beta and activin type 1 receptor kinase. SMAD2 is a receptor-regulated SMAD (R-SMAD). May act as a tumor suppressor in colorectal carcinoma.Riggins G.J., Nat. Genet. 13:347-349(1996)Zhang Y., Nature 383:168-172(1996)Eppert K., Cell 86:543-552(1996)
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of Serine 465(C-S-S(p)-M-S) derived from Human Smad2.
