Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.Argraves W.S., J. Cell Biol. 105:1183-1190(1987)Ota T., Nat. Genet. 36:40-45(2004)Bechtel S., BMC Genomics 8:399-399(2007)
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of tyrosine 795(P-K-Y(p)-E-G) derived from Human ITGB1 .
