Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression. Kitamura D., Nucleic Acids Res. 17:9367-9379(1989)Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databasesOta T., Nat. Genet. 36:40-45(2004)
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 .