The MDC1 protein contains a forkhead homology-associated (FHA) domain and 2 BRCA1 (MIM 113705) C-terminal motifs (BRCTs) and is required for the intra-S-phase DNA damage checkpoint.Nagase T., DNA Res. 3:17-24(1996)Shiina T., Genetics 173:1555-1570(2006)Mungall A.J., Nature 425:805-811(2003)
应用类型
IHC
免疫原
Peptide sequence around phosphorylation site of Serine 513(E-R-S(p)-Q-A) derived from Human MDC1.
