CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain. Miki Y., Science 266:66-71(1994)Smith T.M., Genome Res. 6:1029-1049(1996)Wilson C.A., Oncogene 14:1-16(1997)
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of threonine 509 (S-V-T(p)-P-K) derived from Human CRMP-2.
