cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encode dprotein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
应用类型
IHC
免疫原
Peptide sequence around phosphorylation site of Serine 198(E-F-S(p)-L-K) derived from Human CDC25C.
