FRS2 is an adaptor protein involved in fibroblast growth factor receptor (FGFR) signaling. Plays an important role in linking FGFR and nerve growth factor receptors with Ras/MAPK signaling pathways. Xu H., J. Biol. Chem. 273:17987-17990(1998)Meakin S.O., J. Biol. Chem. 274:9861-9870(1999)Dhalluin C., Mol. Cell 6:921-929(2000)
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of tyrosine 436(L-N-Y(p)-I-Q) derived from Human FRS2 .