IRAK1 encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK1 is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.Cao Z., Science 271:1128-1131(1996)Reichwald K., Mamm. Genome 11:182-190(2000)Jensen L.E., J. Biol. Chem. 276:29037-29044(2001).
应用类型
IHC
免疫原
Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1.
