Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.Tapia C., FEBS Lett. 349:307-312(1994)Fish K.J., J. Biol. Chem. 270:14875-14883(1995)Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y(p)-T-F) derived from Human CK-1α.
