Phosphorylates and activates not only PKB/AKT, but also PKA, PKC-zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development.Alessi D.R., Curr. Biol. 7:261-269(1997)Alessi D.R.,Curr. Biol. 7:776-789(1997)Stephens L.R.,Science 279:710-714(1998)
应用类型
IHC
免疫原
Peptide sequence around phosphorylation site of tyrosine 9(A-L-Y(p)-D-A) derived from Human PDK1.