In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.de Backer M.D., Biochem. Biophys. Res. Commun. 197:1601-1608(1993)Fukui K., Biochem. Biophys. Res. Commun. 201:894-901(1994)Sjoeblom T., Science 314:268-274(2006)
应用类型
ICC
免疫原
Peptide sequence around phosphorylation site of Serine 398(S-H-S(p)-R-Q) derived from Human Histamine H1 Receptor .