Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.Katarzyna Modzelewska, J. Biol. Chem., Dec 2006; 281: 37527 - 37535Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006; 291: H2857 - H2863Sangkil Nam, Cancer Res., Oct 2005; 65: 9185 - 9189Norikazu Yamana, Mol. Cell. Biol., Sep 2006; 26: 6844 - 6
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas .
