Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
应用类型
WB
免疫原
Peptide sequence around phosphorylation site of tyrosine 706 (T-D-Y P-Y-R) derived from Human TrkB.
