Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of serine 1070 (R-Y-S(p)-S-D) derived from Human EGFR.
