Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
应用类型
WB,IHC
免疫原
Peptide sequence around phosphorylation site of serine 155(R-M-S(p)-D-E) derived from Human BAD.
